Our mission is to discover and develop better medicines for patients with autoimmune and inflammatory diseases.


Patients with severe autoimmunity deserve treatment options that preserve healthy immune functioning.

Immune cells have specific checkpoint receptors on their surfaces that prevent them from mounting an immune response to normal healthy human cells. In many autoimmune conditions, including systemic lupus erythematosus, multiple sclerosis, Sjogren’s, myositis, and others, these autoimmune checkpoints are disrupted, resulting in disease.

By restoring the activity of these important receptors, Octagon can restore healthy immune homeostasis without damaging the immune system.


Octagon leverages insights into the glycoproteome to discover important disease-driving biology.

Contact us to learn more about discovery partnership opportunities.